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Medical Biophysics
| Medical Biophysics 302E, General Biophysics | |
| | Description: The physics of blood flow and vascular mechanics, interactions at biological interfaces, and diffusive and convective transport. Experimental methodology is emphasized including quantitative stereology and medical imaging using ultrasound, digital subtraction angiography, and magnetic resonance spectroscopy and imaging, as well as a six-week laboratory research project designed by the student. | | Antirequisite(s): Medical Biophysics 333F, 335G, the former Biology 302, Medical Biophysics 302. | | Prerequisite(s): Biology 022 or 023; ; ; Calculus 050a/b; Physics 020, 024, 025, 028a/b and 029a/b, or the former Physics 022. | | Open to second-year students with an overall average of at least 78% in first year. | | 2 lecture hours, 3 laboratory hours, 1.0 course. | | Enrolment limited; priority to students requiring course for Medical Biophysics programs. | | back to top |
| Medical Biophysics 303E, Biophysical Analysis | |
| | Description: The application of physics, engineering, and mathematical methods to biological mechanisms. Emphasis on modeling, and on problem solving. Special topics include linear systems and biological feedback, analysis of microvascular blood flow, modeling of drug kinetics and oxygen diffusion to heart valves, cornea and tumors, Fourier analysis in imaging systems. | | Antirequisite(s): The former Biology 303, Medical Biophysics 303. | | Prerequisite(s): Calculus 050a/b plus one of 051a/b or 081a/b, or Applied Mathematics 026; Physics 020, 024, 025, 028a/b and 029a/b, or the former Physics 022. Open to second-year students with an overall average of at least 78% in first year. | | 2 lecture hours, 2 laboratory/tutorial hours, 1.0 course. | | back to top |
| Medical Biophysics 330F, Human and Animal Biomechanics | |
| | Description: The mechanical properties of biological structures and fluids in relation to function: deformability, strength, and visco-elasticity of hard and flexibile tissues, modes of loading and failure. Special topics include mechanics of synovial joints, concussion and head injuries, animal flight, and aquatic propulsion. | | Antirequisite(s): The former Biology 330a, Medical Biophysics 330a. | | Prerequisite(s): Calculus 050a/b; Biology 022 or 023; ; Physics 020, 024, 025, 028a/b and 029a/b, or the former Physics 022. Open to second-year students with an overall average of at least 70% in first year. | | 2 lecture hours, 3 laboratory/tutorial hours, 0.5 course. | | back to top |
| Medical Biophysics 331G, Human and Animal Interactions with the Physical Environment | |
| | Description: Examination of the physical processes in the environment that affect life, and physical processes in animals and man that enable them to survive. Topics include pressure, temperature, light, gravity, sound, ionizing and nonionizing radiation. Special topics: heat exchange, vision and hearing, altitude and diving, the space environment, and radiation tolerance. | | Antirequisite(s): The former Biology 331G. | | Prerequisite(s): Biology 022 or 023; ; Physics 020, 024, 025, 028a/b and 029a/b, or the former Physics 022. Open to second-year students with an overall average of at least 70% in first year. | | Corequisite(s): Calculus 050a/b plus one of Calculus 051a/b or 081a/b, or Applied Mathematics 026. | | 3 lecture hours, 0.5 course. | | back to top |
| Medical Biophysics 333F, Biophysics of Transport Systems | |
| | Description: The physics of blood flow and vascular mechanics in the microcirculation and large vessels, surface energy and interactions at biological interfaces such as the lung, diffusive and convective transport and exchange. | | Antirequisite(s): Medical Biophysics 302E (formerly Biology 302). | | Prerequisite(s): Calculus 050a/b or Applied Mathematics 026; Physics 020, 024, 025, 028a/b and 029a/b, or the former Physics 022. Open to second-year students with an overall average of at least 70% in first year. | | 2 lecture hours, 2 tutorial hour, 0.5 course. | | back to top |
| Medical Biophysics 335G, Introductory Medical Imaging | |
| | Description: Image capture and analysis techniques including quantitative stereology and medical imaging using ultrasound, digital subtraction angiography, and magnetic resonance spectroscopy and imaging. | | Antirequisite(s): Medical Biophysics 302E (formerly Biology 302). | | Prerequisite(s): Calculus 050a/b plus one of 051a/b or 081a/b, or Applied Mathematics 026; Physics 020, 024, 025, 028a/b and 029a/b, or the former Physics 022. Open to second-year students with an average of at least 70% in first year. | | 2 lecture hours, 2 tutorial hour, 0.5 course. | | back to top |
| Medical Biophysics 402a/b, Biological Control Systems | |
| | Description: An introduction to linear systems and control theory as applied to organ system regulation and adaptation. Emphasis is placed on biophysical models of the respiratory and cardiovascular systems, and interactions with medical devices. | | Prerequisite(s): Medical Biophysics 302E, 303E; Physics 201a/b and 202a/b or the former Physics 200; Calculus 250a/b or 280a/b, plus one of Calculus 251a/b or 281a/b, or permission of the Department. | | 2 lecture hours, 0.5 course. | | back to top |
| Medical Biophysics 409a/b, Digital Image Processing | |
| | Description: An introduction to the fundamentals of digital image processing including image representation, 2D linear systems theory and Fourier analysis, digital filtering and segmentation. Concentrates on practical techniques through an exposure to image processing applications in industry, science and medicine and assignments based on MATLAB numeric computation and visualization environments. | | Prerequisite(s): Medical Biophysics 302E or 335G, 303E; Physics 201a/b and 202a/b or the former Physics 200; Calculus 250a/b or 280a/b, plus one of Calculus 251a/b or 281a/b, or permission of the Department. | | 2 lecture hours, 0.5 course. | | back to top |
| Medical Biophysics 467a/b, Radiobiology and Radionuclides | |
| | Description: Nature and effects of ionizing radiation on biomolecular structures and living cells, applied radiobiology and radionuclides. Genetic effects of ionizing radiation and methods of protection. Radiobiological applications in modern cancer therapy. | | Antirequisite(s): The former Biophysics 467a/b. | | Prerequisite(s): Medical Biophysics 302E or 333F; Physics 201a/b and 202a/b or the former Physics 200, or permission of the Department. | | 2 lecture hours, 0.5 course. | | back to top |
| Medical Biophysics 470a/b/y, Hemodynamics | |
| | Description: Fundamentals of steady and pulsatile blood flow in tubes and blood vessels. Hemodynamic models and the role of non-dimensional parameters. Measurement of pressure, flow velocity and distribution. Characteristics of flow in large and small blood vessels: geometric factors, measurement techniques and physical alteration of flow by disease. | | Antirequisite(s): The former Biophysics 470a/b/y. | | Prerequisite(s): Medical Biophysics 302E or 333F and 335G, 303E; Physics 201a/b or the former Physics 200 or permission of the Department. | | 2 lecture hours, 0.5 course. | | back to top |
| Medical Biophysics 475a, Medical Imaging | |
| | Description: Physical principles underlying medical imaging. Modalities covered: x-rays, computed tomography, nuclear medicine, ultra-sound, and magnetic resonance imaging. Topics include signal generation, detection and the associated mathematics to produce medically useful images, and factors affecting resolution and sensitivity. | | Antirequisite(s): The former Biophysics 475a. | | Prerequisite(s): Medical Biophysics 302E or 335G, 303E; Physics 201a/b and 202a/b or the former Physics 200 or permission of the Department. | | 3 lecture hours, 0.5 course. | | back to top |
| Medical Biophysics 480, Projects in Biophysics | |
| | Description: Major laboratory course in experimental biophysics for fourth-year Honors Medical Biophysics. The three components are: a major experimental project (topic and advisor chosen in consultation with the student), scientific communication (student presentation and reports), and electronic information processing (data capture, computer analysis of biophysical signals). | | Antirequisite(s): The former Biophysics 480. | | Prerequisite(s): Permission of the Department. | | 15 hours weekly on average, 1.5 course. | | back to top |
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