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Academic Calendar 2010 UNDERGRADUATE COURSE INFORMATION Medical Biophysics (M)
INTRODUCTION
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ACADEMIC INFORMATION
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UNDERGRADUATE COURSE INFORMATION
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TABLE OF CONTENTS




Medical Biophysics (M)

Note:  In order to find a course in the new 4 digit numbering system using an old 3 digit number, please refer to the conversion list below. Before registering for courses with the new 4 digit numbering system, please ensure that you have not previously taken the course in its 3 digit form.

Click here for conversion list of former 3-digit course numbers.

Medical Biophysics 2128A/B - Fundamental Concepts of Medical Imaging
Fundamental concepts in medical imaging, including atomic physics, nuclear physics, and sound and electromagnetic waves. These topics are discussed with an emphasis on basic medical sciences applications, including their role in X–ray computed tomography, mammography, positron emission tomography, ultrasound, and magnetic resonance imaging.
Antirequisite(s): Physics 1301A/B, 1302A/B, 1401A/B, 1402A/B, 1501A/B, 1502A/B, 2101A/B, 2102A/B, 2128A/B, 2600A/B, the former Physics 1020, 1024, 1026, or 222a/b.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 3 lecture hours, 0.5 course.
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Medical Biophysics 2129A/B - Research and Problem-Solving Techniques in Biophysics.
Research and problem-solving strategies are applied to topics in biophysics. These include vector principles, molecular spectroscopy and lasers, advanced microscopy with a focus on methodology and resolution, non–equilibrium effects at membranes and in homeostasis with an overview of the role of partial derivatives, data and error analysis.
Antirequisite(s): Physics 1301A/B, 1302A/B, 1401A/B, 1402A/B, 1501A/B, 1502A/B, 2101A/B, 2102A/B, 2129A/B, the former Physics 1020, 1024, 1026, or 222a/b.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 3 lecture hours, 0.5 course.
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Medical Biophysics 3330F/G - Human & Animal Biomechanics
The mechanical properties of biological structures and fluids in relation to function: deformability, strength, and visco-elasticity of hard and flexible tissues, modes of loading and failure. Special topics include mechanics of synovial joints, concussion and head injuries, and mechanics of orthopedic implants and joint replacement.
Antirequisite(s):
Prerequisite(s): One of Calculus 1000A/B, 1100A/B, Mathematics 1225A/B, Applied Mathematics 1413 or the former Mathematics 030; one of Biology 1001A or 1201A and one of Biology 1002B or 1202B, or the former Biology 1222 or 1223; one of Physics 1028A/B, 1301A/B, 1401A/B or 1501A/B, and one of Physics 1029A/B, 1302A/B, 1402A/B or 1502A/B, or one of the former Physics 1020, 1024 or 1026. Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 3 laboratory/tutorial hours, 0.5 course.
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Medical Biophysics 3336F/G - Human & Animal Interactions with the Physical Environment
Examination of the physical processes in the environment that affect life, and physical processes in animals and man that enable them to survive. Topics include pressure, temperature, light, gravity, sound, ionizing and nonionizing radiation. Special topics: heat exchange, vision and hearing, altitude and diving, the space environment, and radiation tolerance.
Antirequisite(s):
Prerequisite(s): One of Biology 1001A or 1201A and one of Biology 1002B or 1202B, or the former Biology 1222 or 1223; one of Physics 1028A/B, 1301A/B, 1401A/B or 1501A/B, and one of Physics 1029A/B, 1302A/B, 1402A/B or 1502A/B, or one of the former Physics 1020, 1024 or 1026. Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Corequisite(s):
Pre-or Corequisite(s): Calculus 1000A/B or 1100A/B plus one of Calculus 1301A/B or 1501A/B, or Applied Mathematics 1413.
Extra Information: 2 lecture hours, 1 tutorial hour, 0.5 course.
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Medical Biophysics 3501F - Biophysics of Transport Systems
The physics of blood flow and vascular mechanics in the microcirculation and large vessels, surface energy and interactions at biological interfaces such as the lung, diffusive and convective transport and exchange.
Antirequisite(s): The former Medical Biophysics 3302E.
Prerequisite(s): One of Calculus 1000A/B, 1100A/B, Mathematics 1225A/B, Applied Mathematics 1413 or the former Mathematics 030; one of Physics 1028A/B, 1301A/B, 1401A/B or 1501A/B, and one of Physics 1029A/B, 1302A/B, 1402A/B or 1502A/B, or one of the former Physics 1020, 1024 or 1026. Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 1 tutorial hour, 0.5 course.
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Medical Biophysics 3503G - Fundamentals of Digital Imaging
Concepts of images relevant to all imaging modalities. Image formation and capture including digital cameras and the eye, pixels, aliasing, resolution, contrast, sensitivity, specificity, ROC, window/level, dynamic range, RGB, spectroscopy. Image compression and quality, quantitative analysis based on imaging software and principles of quantitative stereology.
Antirequisite(s):
Prerequisite(s): Calculus 1000A/B or 1100A/B plus one of Calculus 1301A/B or 1501A/B, or Applied Mathematics 1413 or the former Mathematics 030; one of Physics 1028A/B, 1301A/B, 1401A/B or 1501A/B, and one of Physics 1029A/B, 1302A/B, 1402A/B or 1502A/B, or one of the former Physics 1020, 1024 or 1026. Typically taken in third year, this course is also open to second-year students with an average of at least 70% in first year.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 1 tutorial hour, 0.5 course.
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Medical Biophysics 3505F - Mathematical Transform Applications in Medical Biophysics
The role of mathematical tranforms in biomedical research. Application of Fourier Transforms for imaging and image analysis. Applications of systems analysis and Laplace Transforms to model complex systems, and of linear time-invariant systems and kinetic models to analyze physiological processes.
Antirequisite(s): The former Medical Biophysics 3303E.
Prerequisite(s): One of Calculus 1000A/B or 1100A/B plus one of Calculus 1301A/B or 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, 1301A/B, 1401A/B or 1501A/B, and one of Physics 1029A/B, 1302A/B, 1402A/B or 1502A/B, or one of the former Physics 1020, 1024 or 1026. Although typically taken in third year, this course is available to second-year students with an overall average of at least 70% in first year.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 2 laboratory/tutorial hours, 0.5 course.
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Medical Biophysics 3507G - Analysis of Oxygen Transport in Biological Systems
The application of physics and mathematics for modeling oxygen transport. Emphasis on problem solving and simple MATLAB computer models for enhancing the students’ interpretation of analytical solutions. Topics include the Krogh-Erlang capillary model, microvascular blood flow, oxygen diffusion in thin tissues and tumors, and finite difference models in unsteady-state systems.
Antirequisite(s): The former Medical Biophysics 3303E.
Prerequisite(s): One of Calculus 1000A/B or 1100A/B plus one of Calculus 1301A/B or 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, 1301A/B, 1401A/B or 1501A/B, and one of Physics 1029A/B, 1302A/B, 1402A/B or 1502A/B, or one of the former Physics 1020, 1024 or 1026.  Although typically taken in third year, this course is available to second-year students with an overall average of at least 70% in first year.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 2 laboratory/tutorial hours, 0.5 course.
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Medical Biophysics 3970Z - General Biophysics Laboratory
Intended primarily for students in Honors Specialization and Major modules in Medical Biophysics. Laboratories include topics from biomechanics (mechanical properties of arteries and bone), imaging (quantitative stereology, optical CT), biophysical analysis (diffusion and washout models), and transport systems (cardiovascular fluid dynamics). Includes an individual 6-week project in a research laboratory.
Antirequisite(s): The former Medical Biophysics 3302E.
Prerequisite(s):
Corequisite(s):
Extra Information: 3 laboratory hours (3 laboratory hours every other week and up to 3 tutorial hours, at the instructor's discretion, in alternate weeks).
0.5 course spanning both the Fall and Winter terms.
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Medical Biophysics 4445A/B - Digital Imaging Processing
An introduction to the fundamentals of digital image processing including image representation, 2D linear systems theory and Fourier analysis, digital filtering and segmentation. Concentrates on practical techniques through an exposure to image processing applications in industry, science and medicine and assignments based on MATLAB numeric computation and visualization environments.
Antirequisite(s):
Prerequisite(s): Medical Biophysics 3503G or the former Medical Biophysics 3302E; Medical Biophysics 3505F and 3507G, or the former Medical Biophysics 3303E; Calculus 2303A/B or 2503A/B; 1.0 course from Medical Biophysics 2128A/B and 2129A/B, or Physics 2128A/B and 2129A/B, or Physics 2101A/B and 2102A/B, or permission of the department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Medical Biophysics 4455A/B - Biological Control Systems
An introduction to linear systems and control theory as applied to organ system regulation and adaptation. Emphasis is placed on biophysical models of the respiratory and cardiovascular systems, and interactions with medical devices.
Antirequisite(s):
Prerequisite(s): Medical Biophysics 3501F or the former Medical Biophysics 3302E; Medical Biophysics 3505F or the former Medical Biophysics 3303E; or permission of the department
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 3 lecture hours, 0.5 course.
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Medical Biophysics 4467A/B - Radiation Biology with Medical Applications
Nature and effects of ionizing radiation on biomolecular structures, living cells and tissues. Genetic effects and methods of radiation protection. Radiobiological implications of diagnostic and therapeutic radiation.
Antirequisite(s):
Prerequisite(s): Medical Biophysics 3501F or the former Medical Biophysics 3302E; 1.0 course from Medical Biophysics 2128A/B and 2129A/B, or Physics 2128A/B and 2129A/B, or Physics 2101A/B and 2102A/B, or permission of the department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Medical Biophysics 4475A/B - Medical Imaging
Physical principles underlying medical imaging. Modalities covered: x-rays, computed tomography, nuclear medicine, ultra-sound, and magnetic resonance imaging. Topics include signal generation, detection and the associated mathematics to produce medically useful images, and factors affecting resolution and sensitivity.
Antirequisite(s):
Prerequisite(s): Medical Biophysics 3503G or the former Medical Biophysics 3302E; Medical Biophysics 3505F and 3507G, or the former Medical Biophysics 3303E; 1.0 course from Medical Biophysics 2128A/B and 2129A/B, or Physics 2128A/B and 2129A/B, or Physics 2101A/B and 2102A/B, or permission of the department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 3 lecture hours, 0.5 course.
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Medical Biophysics 4535A/B - Hemodynamics
Biophysics related to blood flow: Biomechanical properties of blood, heart, arteries, and veins; pressure, flow, and Poiseulle's law; optimality principles; fluid flow conservation laws and their mathematical description; pulsatile flow in rigid vessels; wave propagation in elastic vessels; structure and blood rheology of the microcirculation; oxygen delivery and flow regulation.
Antirequisite(s):
Prerequisite(s): Medical Biophysics 3501F and 3503G, or the former Medical Biophysics 3302E; Medical Biophysics 3505F and 3507G, or the former Medical Biophysics 3303E; 1.0 course from Medical Biophysics 2128A/B and 2129A/B, or Physics 2128A/B and 2129A/B, or Physics 2101A/B and 2102A/B, or permission of the department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Medical Biophysics 4970E - Research Projects in Biophysics
Major laboratory course in experimental biophysics for fourth-year Honors Specialization Medical Biophysics. The three components are: a major experimental project (topic and advisor chosen in consultation with the student), scientific communication (student presentation and reports), and electronic information processing (data capture, computer analysis of biophysical signals).
Antirequisite(s):
Prerequisite(s): Medical Biophysics 3970Z and registration in Year 4 of an Honors Specialization offered by the Department of Medical Biophysics.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 15 hours weekly on average, 1.5 course.
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Academic Calendar 2010 UNDERGRADUATE COURSE INFORMATION Medical Biophysics (M)
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