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Academic Calendar 2008 UNDERGRADUATE COURSE INFORMATION Pharmacology and Toxicology (M)
INTRODUCTION
UNDERGRADUATE SESSIONAL DATES
STUDENT SERVICES
ACADEMIC INFORMATION
STUDENT FINANCIAL SERVICES
FACULTIES
UNDERGRADUATE COURSE INFORMATION
FACULTY MEMBERS
AFFILIATED UNIVERSITY COLLEGES
GLOSSARY
NEW MODULES/PROGRAMS
TABLE OF CONTENTS
Pharmacology and Toxicology (M)

Note:  In order to find a course in the new 4 digit numbering system using an old 3 digit number, please refer to the conversion list below. Before registering for courses with the new 4 digit numbering system, please ensure that you have not previously taken the course in its 3 digit form.

Click here for conversion list of former 3-digit course numbers.

 
Pharmacology and Toxicology 2060A/B - Introductory Pharmacology and Therapeutics
A course for students in the BSc in Nursing and other Health Sciences programs as well as students in BMSc and BSc programs, to provide a basic understanding of the fundamentals of drug action and the mechanisms of action and therapeutic use of the important classes of drugs.
Prerequisite(s):
Corequisite(s):
Pre-or Corequisite(s): Biochemistry 2280A and Chemistry 2213A/B or registration in the BSc in Nursing or the Health Information Management program in the Faculty of Health Sciences.
Extra Information: 3 lecture hours, 1 tutorial hour (optional), 0.5 course.
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Pharmacology and Toxicology 3550A/B - Principles of Drug Action
This course will examine how drugs reach their intended targets, how they act and how their activities are terminated. Established drugs and novel therapeutic agents will be used as examples. Focus will be placed on interaction of drugs with specific receptors.
Antirequisite(s): The former Pharmacology and Toxicology 357
Prerequisite(s): Biochemistry 2280A or the permission of the Department. Biology 2382B and Chemistry 2223B are highly recommended.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 1 tutorial hour, 0.5 course.
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Pharmacology and Toxicology 3560A/B - Introductory Toxicology
Fundamentals of how chemicals produce toxicity in biological systems with application of underlying principles in environmental control and chemical poisoning. Included are aspects of dose-response relationship; physiological and biochemical processes involved in handling of toxicants following exposure; mechanisms of toxic action and their modification by chemical, environmental and biological factors.
Antirequisite(s): The former Pharmacology and Toxicology 357
Prerequisite(s): Biochemistry 2280A; Chemistry 2213A/B or the former Chemistry 226a/b, or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 1 tutorial hour, 0.5 course.
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Pharmacology and Toxicology 3580Y - Pharmacology & Toxicology Laboratory
A series of laboratory exercises, tutorials and presentations which introduce students to some of the basic approaches used in Pharmacology and Toxicology.
Antirequisite(s): The former Pharmacology and Toxicology 357
Prerequisite(s): Biochemistry 2280A and Chemistry 2213A/B, or permission of the Department. A minimum average of 75% in the previous year is required.
Pre-or Corequisite(s):
Extra Information: Enrolment limited.
3 laboratory hours (3 laboratory hours every other week and up to 3 tutorial hours, at the instructor's discretion, in alternate weeks). 0.5 course
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Pharmacology and Toxicology 4320A/B - Cardiovascular Pharmacology
Basic principles of cardiovascular pharmacology with particular emphasis on cellular mechanisms of drug action and mechanisms of therapeutic efficacy in disease states.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3550A/B and 3580Y, or the former Pharmacology and Toxicology 357, or Physiology 3120, or the former Physiology 310; or Pharmacology and Toxicology 3550A/B and registration in Year 4 of a module in Pathology and Toxicology, or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology and Toxicology 4340A/B - Gene Expression Pathways in Drug Discovery
This course explores how drugs and endogenous compounds mediate their biological effects through nuclear signalling pathways. The emphasis will be on aspects of gene regulation and signalling by nuclear signalling pathways. The emphasis will be on aspects of gene regulation and signalling by metabolism, development and reproduction.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3550A/B, 3560A/B and 3580Y, or the former Pharmacology and Toxicology 357; or Pharmacology and Toxicology 3550A/B and 3560A/B with an average of at least 75% in each of these two half courses; or Pharmacology and Toxicology 3550A/B, 3560A/B and registration in Year 4 of a module in Pathology and Toxicology; or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology and Toxicology 4360A/B - Mechanisms of Cancer Chemotherapy
This course is designed to give students a basic understanding of the molecular pharmacology and therapeutic properties of anticancer agents. The focus is on molecular mechanisms of cancer chemotherapy, and will include drug resistance and the roles of receptor kinases and G protein-coupled receptors in existing and novel cancer therapies.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3550A/B, 3560A/B and 3580Y (or the former Pharmacology and Toxicology 357); or Pharmacology and Toxicology 3550A/B and registration in Year 4 of a module in Pathology and Toxicology, or permission from the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology and Toxicology 4380A/B - Neuropharmacology
This course will focus on the cellular and molecular mechanisms underlying the actions of drugs on the central and peripheral nervous systems. The focus will be on recent developments in the field of neuroscience and their impact on our understanding of the actions, and development of, new drugs.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3550A/B and 3580Y (or the former Pharmacology and Toxicology 357) and Physiology 3140A; or Pharmacology and Toxicology 3550A/B and Physiology 3140A and registration in Year 4 of a module in Pathology and Toxicology, or permission from the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology and Toxicology 4430A/B - Pharmacology and Toxicology of Natural-Sourced Medicines
Contemporary use of medicines derived from natural sources. Regulatory aspects of their use and the scientific basis for assessment of efficacy, quality, and safety of these products will be discussed. The mechanism(s) of beneficial and harmful effects of selected natural health products, including herb-drug interactions, will be included.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3550A/B, 3560A/B and 3580Y, or the former Pharmacology and Toxicology 357; or Pharmacology and Toxicology 3550A/B and 3560A/B with an average of at least 75% in each of these two half courses; or Pharmacology and Toxicology 3550A/B, 3560A/B and registration in Year 4 of a module in Pathology and Toxicology; or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours per week, 0.5 course.
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Pharmacology and Toxicology 4540A/B - Molecular Physiology and Pharmacology of Cell Proliferation and Tissue Repair
The physiology, pathophysiology and pharmacology of cell proliferation and tissue repair. The course addresses the translation of basic molecular and cellular processes into an understanding of relevant human disorders and clinically useful therapies, through the development of appropriate in vitro and in vivo experimental models.
Antirequisite(s):
Prerequisite(s): Physiology 3120 or the former Physiology 310; Physiology 3140A or Biology 3316A; Pharmacology and Toxicology 3550A/B and 3580Y, or the former Pharmacology and Toxicology 357, or Pharmacology and Toxicology 3550A/B and registration in Year 4 of a module in Pathology and Toxicology, or permission of the Department. Biology 3592A is recommended.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2.0 lecture hours, 0.5 course.
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Pharmacology and Toxicology 4620A - Molecular Mechanisms of Drug Action
This course is focussed on the molecular mechanisms underlying the biological effects of drugs. Content includes: i) advanced drug-receptor theory, ii) theoretical models used to predict drug effects, and iii) chemical structure-activity relationships and modern receptor structure-function analyses as they relate to drug action.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3550A/B and 3580Y, or the former Pharmacology and Toxicology 357; or Pharmacology and Toxicology 3550A/B with an average of at least 75%; or Pharmacology and Toxicology 3550A/B and registration in Year 4 of a module in Pathology and Toxicology, or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology and Toxicology 4630A - Principles of Toxicology
Advanced studies on how chemicals produce undesirable effects in biological systems. Case study and problem-solving approaches will be used to illustrate underlying principles that govern the disposition of toxic chemical agents and dose-response relationship. Biochemical and molecular mechanisms of various forms of chemical toxicities will be examined.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3560A/B and 3580Y, or the former Pharmacology and Toxicology 357; or Pharmacology and Toxicology 3560A/B and registration in Year 4 of a module in Pathology and Toxicology, or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology and Toxicology 4660A/B - Human Toxicology
A course dealing with the pharmacological and toxicological principles underlying the adverse effects of xenobiotics in humans. In addition to reviewing mechanisms of toxicity in humans, the course will include overviews of the principles of management of human poisoning, the principles of chronic toxicity and of drug safety in humans.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3560A/B and 3580Y, or the former Pharmacology and Toxicology 357; or Pharmacology and Toxicology 3560A/B with an average of at least 75%; or Pharmacology and Toxicology 3560A/B and registration in Year 4 of a module in Pathology and Toxicology, or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course
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Pharmacology and Toxicology 4980E - Experimentation and Communication in Pharmacology and Toxicology
Course requirements: i) theory and practice of modern laboratory techniques, laboratory safety, appropriate use of experimental models, ii) independent research project supervised by faculty, iii) scientific communication consisting of instruction on communication skills, preparation of seminar, poster presentation and preparation of a research proposal and final research project written report.
Antirequisite(s):
Prerequisite(s): Pharmacology and Toxicology 3550A/B, 3560A/B and 3580Y, or the former 357; Physiology 3120 or the former 310; Physiology 3140A; and registration in either an Honors Specialization in Pharmacology and Toxicology or Honors Specialization in Physiology and Pharmacology.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: Minimum 11 laboratory hours per week plus 2 seminar hours on alternate weeks, 1.5 course.
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Academic Calendar 2008 UNDERGRADUATE COURSE INFORMATION Pharmacology and Toxicology (M)
Decision Academic