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Biochemistry
2280A -
Biochemistry and Molecular Biology
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An introduction to biochemistry with emphasis on protein structure and function, intermediary metabolism and nucleic acid structure and function.
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Biochemistry
2288A -
Biochemistry and Molecular Biology for Foods and Nutrition
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An introduction to biochemistry with emphasis on protein structure and function, intermediary metabolism and nucleic acid structure and function.
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Biochemistry
3380G -
Biochemistry Laboratory
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This course consists of a series of laboratory exercises designed to familiarize the student with the basic methods in biochemistry and molecular biology, and to demonstrate concepts taught in biochemistry lecture courses. Students will learn how to present their results in an acceptable scientific format.
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Biochemistry
3381A -
Biological Macromolecules
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A consideration of the structure of proteins and nucleic acids; enzymology; elements of recombinant DNA technology and related methodology.
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Biochemistry
3382A -
Biochemical Regulation
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Among the topics discussed will be principles of metabolic control, mechanisms of signal transduction, regulation of DNA replication, regulation of gene expression, and epigenetic mechanisms of gene regulation.
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Biochemistry
3383F/G -
Introduction to Biochemical Research
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Students carry out a research project under the direction of a faculty member, gaining practical experience in a biochemistry research laboratory. Experimental design, critical thinking, and scientific communication will be emphasized, and students will develop skills at reading and reviewing primary scientific literature.
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Permission of the Department.
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Biochemistry
3385A -
Human Biochemistry
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A course dealing with Biochemical aspects of the human condition. Topics in human disease, medical testing, and lifestyle will be considered in a clinical-case-oriented fashion. The emphasis will be on structural and metabolic issues related to carbohydrates, lipids, vitamins, minerals, nucleic acids and proteins.
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Biochemistry
3386B -
Clinical Biochemistry
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The application of biochemical and molecular principles to the analytical components used to select, evaluate and interpret tests for clinical diseases. Also included will be discussions on the specialized instruments required. Students will gain understanding of the practice of clinical biochemistry, as one of the disciplines of laboratory medicine.
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Biochemistry
3390B -
Advanced Methods for Biochemistry
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Students will explore the chemical and physical underpinnings of biochemical phenomena by solving practical, real-world, quantitative problems. Students will learn how to answer biochemical research questions by applying advanced experimental strategies and techniques, including methods in bioinformatics and the mining of biochemical databases.
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Biochemistry
4410A -
Molecular Biology of DNA and RNA
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The use of fundamental techniques in molecular biology and molecular genetics are illustrated using examples from the classic and current literature. Selected topics include eukaryotic gene cloning, transgenic animals, rational drug design, DNA replication and cell cycle regulation.
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Biochemistry
4415B -
Applications of Synthetic Biology and Chemical Genetics in Medicine
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This course will explore how metabolic pathways are currently being re-engineered in microorganisms to produce drugs that are otherwise difficult to manufacture. We will also investigate how drug targets are being identified using newly developed chemical genetic screening methods. The impact of both approaches on medicine will be evaluated.
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Biochemistry
4420A -
Molecular Biology of Proteins
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Topics to be considered at an advanced level will include: translation, folding and assembly, targeting, turnover, structure and motifs.
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The former Biochemistry 4420B.
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Biochemistry
4425B -
Proteomics and Protein Biotechnology
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The course will cover applied aspects of protein chemistry in biotechnology and protein design. Topics covered will include applications of modern analytical and biophysical techniques used in proteomics and related biochemical analyses, protein structure design, and antibody engineering.
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Biochemistry
4450A -
Molecular Genetics of Human Cancer
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Key cellular pathways that are frequently subverted in tumour cells leading to neoplasia will be discussed, as well as mechanisms by which environmental factors affect tumour development. Cancer models and molecular therapies will also be considered.
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Biochemistry
4463G -
Biochemistry of Genetic Diseases
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In this course, knowledge of molecular biology and biochemistry is applied to the understanding of human genetic diseases. Topics of current interest are used as examples to study the transition from mutations to clinical disorders. Societal and ethical issues are discussed.
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Biochemistry
4483E -
Research Project and Seminar
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The major laboratory course for the Honors Specialization in Biochemistry and Honors Specialization modules combined with Biochemistry. Lectures on laboratory safety, biosafety, use of animals in research, scientific integrity; an independent research project (topic and advisor chosen by consultation between student and faculty); scientific communication (two seminars and a written report).
Prerequisite(s):
Biochemistry 3380G, 3381A and 3382A, with marks in each of at least 70%. Enrolment is limited, and is available only to students in Year 4 of Honors Specialization modules in Biochemistry, Biochemistry and Cell Biology, Biochemistry and Pathology of Human Disease, Biochemistry and Chemistry, Biochemistry of Infection and Immunity, Computational Biochemistry, and Medical Biophysics and Biochemistry. Students in the Honors Specialization in Biochemistry of Infection and Immunity may substitute one of Microbiology and Immunology 3610F, 3620G, or the former 3600G with a minimum mark of 70% in lieu of Biochemistry 3380G as a prerequisite. Students in the Honors Specialization in Computational Biochemistry may substitute Biochemistry 3383F/G with a minimum mark of 70% in lieu of Biochemistry 3380G as a prerequisite.
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Biochemistry
4485E -
Clinical Biochemistry Research Project Seminar
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The major laboratory course for students in the Honors Specialization in Clinical Biochemistry. The course consists of lectures on laboratory safety and scientific integrity; an independent research project (topic and advisor chosen by consultation between student and faculty); scientific communication (two seminars/written report).
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Biochemistry 3381A, 3382A and 3380G or the former 3387G, with marks in each of at least 70%. Priority will be given to students in the Honors Specialization in Clinical Biochemistry.
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Biochemistry
4999E -
Advanced Research in Biochemistry
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This laboratory course is intended for students interested in pursuing graduate-level research. Lectures on literature searches, data mining, and effective communication; an independent research project (topic and advisor chosen by consultation between student and faculty); scientific communication (introduction to topic, mid-year report, seminar).
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